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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLK All Species: 30.3
Human Site: S197 Identified Species: 74.07
UniProt: P51451 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51451 NP_001706.2 505 57706 S197 S P R I T F P S L Q A L V Q H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087480 505 57550 S197 S P R I T F P S L Q A L V Q H
Dog Lupus familis XP_543206 500 56982 T192 S P R I T F P T L Q A L V Q H
Cat Felis silvestris
Mouse Mus musculus P16277 499 56626 T191 S P R I T F P T L Q A L V Q H
Rat Rattus norvegicus P50545 524 59135 S216 S P R S T F S S L Q E L V V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514812 514 58948 C205 S P R I T F T C I S D M I K H
Chicken Gallus gallus P42683 508 58121 S200 S P R V T F S S L H E L V E Y
Frog Xenopus laevis P13406 537 60828 T223 T T R A Q F E T L Q Q L V Q H
Zebra Danio Brachydanio rerio NP_001025391 485 55626 S178 S P S T S F S S L Q E L V K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9J3 517 59051 T199 A R R T T F R T L Q E L V E H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.2 87.9 N.A. 85.9 61 N.A. 61.4 63.9 54.7 64.9 N.A. 51.6 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 95.6 94.4 N.A. 92.6 76.3 N.A. 77 78.5 69 78.2 N.A. 66.9 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 73.3 N.A. 46.6 60 53.3 53.3 N.A. 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 73.3 N.A. 73.3 80 66.6 73.3 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 0 0 0 40 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 40 0 0 20 0 % E
% Phe: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 80 % H
% Ile: 0 0 0 50 0 0 0 0 10 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % K
% Leu: 0 0 0 0 0 0 0 0 90 0 0 90 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 80 0 0 0 0 40 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 80 10 0 0 50 0 % Q
% Arg: 0 10 90 0 0 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 80 0 10 10 10 0 30 50 0 10 0 0 0 0 0 % S
% Thr: 10 10 0 20 80 0 10 40 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 90 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _